The information contained in this section of the site is clinical in nature and specifically created for healthcare professionals.

You are now leaving Orenitram.com.

Click CONTINUE to proceed or CLOSE to return to Orenitram.com.
Taking Orenitram
Adjustable dosing How to take Orenitram Treatment goals Additional considerations

Open up to a dosing plan designed just for you

Taking Orenitram

Orenitram is available in 5 different dose strengths:

Orenitram® (treprostinil) Dosage Options – 0.125 mg, 0.25 mg, 1 mg, 2.5 mg, 5 mg Orenitram® (treprostinil) Dosage Options – 0.125 mg, 0.25 mg, 1 mg, 2.5 mg, 5mg

Five different dose strengths, and the option for either twice-daily or 3-times-daily dosing, allow your doctor more flexibility in finding the exact dose combination that is right for you.

Your dose will be adjusted over time. This will be based on what works best for your PAH symptoms and how you tolerate taking Orenitram.

Orenitram should be taken with food.

Take Orenitram exactly as prescribed by your healthcare provider. If you miss a dose of Orenitram, take the dose as soon as possible with food. If you miss 2 or more doses, call your healthcare provider for instructions.

Looking for more information about Orenitram?

Learn what you need to know about Orenitram, including dosing information and food ideas.

Watch the full video or select the topic that most interests you.

  • Watch the full video
  • Orenitram introduction
  • Your first shipment
  • Taking Orenitram
  • Taking Orenitram with food
  • Support
  • Indication and Important Safety Information

Setting your treatment goals

Setting goals is an important part of your treatment. Your healthcare provider can help you figure out what goals are appropriate for you. They may be related to your daily life or to your ability to enjoy activities with loved ones. Keep track of how you feel after taking your medication, as well as what combination of foods you took along with your medication. Use these notes to discuss how you are feeling with your healthcare provider.

Setting your treatment goals

Setting goals is an important part of your treatment. Your healthcare provider can help you figure out what goals are appropriate for you. They may be related to your daily life or to your ability to enjoy activities with loved ones. Keep track of how you feel after taking your medication, as well as what combination of foods you took along with your medication. Use these notes to discuss how you are feeling with your healthcare provider.

Daily Treatment Diary

Use the Treatment Diary to record your daily Orenitram routine, and share your notes with your healthcare team so they can help guide your treatment.

Download Now

Some important things to remember

Orenitram® (treprostinil) Additional Considerations Orenitram® (treprostinil) Additional Considerations

For additional information, please see Patient Information for Orenitram.

Do not take Orenitram if you have severe liver problems.

Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause your PAH symptoms to worsen.

You may see the tablet shell in your stools (bowel movements). This is normal. The tablet shell is not digested. If you have diverticulosis, Orenitram tablets can lodge in a diverticulum in your intestine.

Next: Resources and support to help you with your treatment

Important Safety Information for Orenitram

Do not take Orenitram if you have severe liver problems.

Before you take Orenitram, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.

Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.

If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.

Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.

The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.

Indication

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.

OREISIdtcJAN16

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Patient Information for Orenitram.

For additional information about Orenitram, call 1-877-UNITHER (1-877-864-8437).

This information is provided for educational purposes only and is not intended as treatment advice. Consult your healthcare provider for treatment advice.

IMPORTANT SAFETY INFORMATION FOR ORENITRAM

Expand

Do not take Orenitram if you have severe liver problems.

Before you take Orenitram, tell your healthcare provider if you:

  • Have liver problems, diverticulosis, or any other medical conditions
  • Are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. You and your healthcare provider should decide if you will take Orenitram or breastfeed. You should not do both

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.

Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.

If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.

Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.

The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.

Indication

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.

OREISIdtcJAN16

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Patient Information for Orenitram.

For additional information about Orenitram, call 1-877-UNITHER (1-877-864-8437).

This information is provided for educational purposes only and is not intended as treatment advice. Consult your healthcare provider for treatment advice.